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Hypertension is the most common modifiable risk factor for cardiovascular disease and death, and lowering blood pressure with antihypertensive drugs reduces target organ damage and prevents cardiovascular disease outcomes.

Most hypertensive patients will need a combination of antihypertensive agents to achieve the therapeutic goals. Recent guidelines recommend initiating treatment with two drugs in those patients with a systolic blood pressure >20 mmHg and/or a diastolic blood pressure >10 mmHg above the goals, and in those patients with high cardiovascular risk. In addition, approximately 25% of patients will require three antihypertensive agents to achieve the therapeutic targets.

Articles

Chronic Thromboembolic and Pulmonary Arterial Hypertension Share Acute Vasoreactivity Properties

Citation:

European Cardiovascular Disease 2006;2(2):1–4

Baroreflex Activation in Drug-resistant Hypertension

Citation:

European Cardiology 2008:4(2):56-8

Time Is of the Essence - A Review of Evidence to Support Rapid Discovery to Treatment for Patients with ST-segment Elevation Myocardial Infarction

Citation:

European Cardiology 2008;4(2):49–50

Adherence to Antihypertensive and Lipid-lowering Therapy - Impact on Clinical Practice

Citation:

European Cardiology 2008;4(2):10–5